This chapter explores little-known aspects of the corporate society of San Miguel de Tucumán by reconstructing the framework of relationships woven by the members of the Cofradía del Santísimo Rosario de la Orden de Predicadores between 1791 and 1809. The impact of the confraternity on socio-religious life in Tucumán is of great scholarly interest. An examination of the Primer libro de la Cofradía del Santísimo Rosario in the Dominican convent specifies the distinctive characteristics of the confraternity, the social connection of its members, and the particular links they established with other social actors, in addition to other aspects. The chapter argues that in keeping with its dynamic development this Dominican confraternity reinforced and complexified the colonial corporate-state framework. Indeed, during the period under consideration, institutional offices of the confraternity were held by members of the local elite, who were in turn related to other city corporations, specially with the cabildo. The theoretical and methodological perspective is inscribed in approaches that developed in Argentine historiography since the restoration of democracy in the 1980s and that have been applied to colonial confraternities and to the development of the church during Spanish domination.